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This service is provided on News Group Newspapers’ Limited’s Standard Terms and Conditions in accordance with our Privacy Cookie Policy. To inquire about a licence to reproduce material, visit our Syndication site. View our online Press Pack. There are some exceptions, but the problem (as always) is that it’s usually impossible to see them coming. Lipitor is the first example that comes to mind ; Warner Lambert just about killed it because it was going to be the umpteenth statin, and they didn’t think its market share would justify the development costs. (I should have mentioned that one back in the first paragraph, when I was talking about shaky market projections!) It was only after the drug got well into the clinic that its potential began to show itself, just as Exubera was far along before its deficiencies became clear..

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